RareWays is a research directory. It helps you understand the science. It is not medical advice. Always discuss your care options with your healthcare team.
Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.
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Oral Submucous Fibrosis: Research Summary
Printed from RareWays (rareways.org)
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Corroborating Ultrasonographic findings of buccal mucosa with clinical and histopathological staging of OSMF: A non-invasive diagnostic approach
Sunita Gupta et al., Journal of International College of Dentists (17 October 2026)
https://doi.org/10.18231/j.jicd.77609.1792216918
- 2.
The METTL3/LOXL2 axis participates in aberrant epithelial-fibroblast crosstalk and induces oral submucous fibrosis in rats.
Fan Shuhang et al., Molecular and cellular biochemistry (16 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42886445/
- 3.
Natural herb efficacy in treatment of Oral Submucous Fibrosis: A systematic review and meta-analysis
Prasangi Madubhashini Peiris et al., Ceylon Journal of Science (13 October 2026)
https://doi.org/10.4038/cjs.v55i4.9648
- 4.
Biofluid based biochemical and clinicopathological profiling for the detection and stratification of oral potentially malignant disorders.
Varyani Ronak A et al., Clinical oral investigations (5 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42832091/
- 5.
Alternate Drug Delivery Systems in the Management of Oral Submucous Fibrosis: A Narrative Review with Emphasis on Oral Mucosal Iontophoresis
Chandwani Dr Roshan Amarlal et al., International Journal Dental and Medical Sciences Research (4 October 2026)
https://doi.org/10.5281/zenodo.23131343
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Oral Submucous Fibrosis
Oral submucous fibrosis is a chronic condition in which the tissues lining the mouth become scarred and stiff. It can cause a burning feeling with spicy food and make it hard to open the mouth fully. It is strongly linked to chewing areca nut (betel quid). Management includes stopping the habit, mouth-opening exercises and medicines, with regular checks because of a raised risk of oral cancer.
This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.
Most Recent Research
Aim and Objectives: To assess the ultrasonographic characteristics of buccal mucosa in patients with oral submucous fibrosis (OSMF) and healthy individuals, and to correlate these findings with clinical and histopathological parameters.Materials and Methods: A high-frequency linear transducer (7.5–12 MHz) was employed for buccal mucosa imaging in 20 healthy controls and 80 OSMF patients. Submucosal thickness measurements and Peak Systolic Value (PSV) assessments were performed using real-time B-mode and color Doppler ultrasonography.Results: Strong correlations were established between different study groups, demonstrating increased submucosal thickness and reduced PSV in OSMF patients compared to healthy controls (p < 0.05). Furthermore, progressive increases in submucosal thickness and corresponding decreases in PSV were observed with advancing histopathological severity.Conclusion: Ultrasonography represents an efficient, non-invasive, radiation-free diagnostic tool for OSMF evaluation and may serve as an initial alternative to invasive biopsy procedures.
Common Questions
What is Oral Submucous Fibrosis?
Oral submucous fibrosis is a chronic condition in which the tissues lining the mouth become scarred and stiff. It can cause a burning feeling with spicy food and make it hard to open the mouth fully. It is strongly linked to chewing areca nut (betel quid). Management includes stopping the habit, mouth-opening exercises and medicines, with regular checks because of a raised risk of oral cancer.
How many clinical trials are available for Oral Submucous Fibrosis?
RareWays currently indexes 11 clinical trials for Oral Submucous Fibrosis, of which 1 is actively recruiting. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.
Where does the research data for Oral Submucous Fibrosis come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.
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