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Coverage: all available years, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.
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You-Hoover-Fong Syndrome: Research Summary
Printed from RareWays (rareways.org)
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Lennox-Gastaut syndrome in a patient with biallelic TELO2 variants.
Odabassian Melissa et al., Epileptic disorders : international epilepsy journal with videotape (1 June 2026)
https://pubmed.ncbi.nlm.nih.gov/41553761/
- 2.
[Analysis of a child with You-Hoover-Fong syndrome due to compound heterozygous variants of the TELO2 gene and a literature review].
Li Pei et al., Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics (10 November 2025)
https://pubmed.ncbi.nlm.nih.gov/41645377/
- 3.
Expansion of the Phenotype of You-Hoover-Fong Syndrome and Possible Increased Risk of Cancer.
De Falco Alessandro et al., American journal of medical genetics. Part A (1 May 2025)
https://pubmed.ncbi.nlm.nih.gov/39704248/
- 4.
The first Iranian patient with You-Hoover-Fong syndrome and a review of the literature on 27 cases: expanding the genotypic and phenotypic spectrum.
Shokrollahi Nima et al., Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (1 August 2024)
https://pubmed.ncbi.nlm.nih.gov/38421525/
- 5.
TELO2 ‐related syndrome ( You‐Hoover‐Fong syndrome): Description of 14 new affected individuals and review of the literature
Daniah Albokhari et al., American Journal of Medical Genetics Part A (16 February 2023)
https://doi.org/10.1002/ajmg.a.63142
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
You-Hoover-Fong Syndrome
You-Hoover-Fong syndrome is a very rare genetic condition caused by changes in both copies of the TELO2 gene. It affects brain development, leading to intellectual disability, delayed milestones and poor muscle tone, and it can also involve a small head size, eye and hearing problems, and distinctive facial features. There is no specific treatment, so care focuses on therapies, developmental support and managing individual symptoms.
This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.
You-Hoover-Fong Syndrome is very rare and little research has been published, so this page includes research from every year, including case reports about individual patients. Case reports are marked, and describe one person's experience rather than tested results.
Most Recent Research
Common Questions
What is You-Hoover-Fong Syndrome?
You-Hoover-Fong syndrome is a very rare genetic condition caused by changes in both copies of the TELO2 gene. It affects brain development, leading to intellectual disability, delayed milestones and poor muscle tone, and it can also involve a small head size, eye and hearing problems, and distinctive facial features. There is no specific treatment, so care focuses on therapies, developmental support and managing individual symptoms.
How many clinical trials are available for You-Hoover-Fong Syndrome?
No clinical trials are currently indexed for You-Hoover-Fong Syndrome. This may change as new trials are registered. Check back regularly or visit ClinicalTrials.gov directly.
Where does the research data for You-Hoover-Fong Syndrome come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.
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