Spinocerebellar Ataxia — Research Summary
Printed from RareWays (rareways.com.au) on 11 June 2026
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Densification pretreatment using ternary phenolic DES enables efficient biomass fractionation and selective lignin arylation modification.
Yuan Xinchuan et al. — Bioresource technology (1 June 2026)
https://pubmed.ncbi.nlm.nih.gov/41819351/
- 2.
Performance, carcass traits and meat quality of lambs fed sugarcane silage (Saccharum officinarum) with or without Tithonia diversifolia.
Marques Natana Mendes et al. — Meat science (1 June 2026)
https://pubmed.ncbi.nlm.nih.gov/41723907/
- 3.
Effects of different exercise modalities on four major neurodegenerative diseases and their molecular mechanisms.
Wang Shuo et al. — Neuroscience (7 May 2026)
https://pubmed.ncbi.nlm.nih.gov/41796789/
- 4.
Metformin improves RAN protein pathology, alternative splicing, and behavioral phenotypes in SCA8 mice.
Romano Lisa El et al. — Life science alliance (1 May 2026)
https://pubmed.ncbi.nlm.nih.gov/41771688/
- 5.
Novel dipotassium oxalate-containing mouth rinses for the prevention of erosive tooth wear.
Scontre Luiza Santos et al. — Journal of dentistry (1 May 2026)
https://pubmed.ncbi.nlm.nih.gov/41765223/
Clinical Trials — Currently Recruiting (Australia)
Ask your doctor whether you or your child may be eligible for any of these trials.
- 1.
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
Recruiting — SCAD Alliance
https://clinicaltrials.gov/study/NCT04496687
- 2.
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Recruiting — Sanford Health
https://clinicaltrials.gov/study/NCT01793168
- 3.
Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2
Recruiting — Phase 1 — Arrowhead Pharmaceuticals
https://clinicaltrials.gov/study/NCT06672445
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Spinocerebellar Ataxia
Spinocerebellar Ataxia refers to a group of inherited progressive neurological disorders characterised by degeneration of the cerebellum and its connections, causing difficulty walking, poor coordination, and speech problems. More than 40 genetic subtypes have been identified. There is currently no disease-modifying treatment, but active clinical trials are under way.
Most Recent Research
Acid deep eutectic solvent (DES)-mediated delignification causes much polysaccharide (especially xylan) degradation, compromising biomass upgrading efficiency. To tackle this issue, a ternary DES densification pretreatment (betaine-guaiacol-salicylic acid, BE-GUA-SCA) was developed, enabling efficient lignin removal and high sugar retention, yielding 73.1% delignification with preservation of 98% glucan and 85% xylan under optimal conditions. Guaiacol spontaneously polymerized with Cα in lignin's β-aryl ether during pretreatment, forming a guaiacolated structure that blocked undesirable condensation. The resulting arylated lignin enriched phenolic hydroxyls and retained β-aryl ethers. Moreover, this ternary DES system showed excellent recyclability (94.42% DES recovery and 96.19% DES purity after 5 cycles) and superior functional stability (>70% delignification, over 90% glucan recovery and 80% xylan recovery after 5 cycles), overcoming traditional acidic catalysis limitations and offering a novel strategy for selective lignin functionalization and polyphenol derivative synthesis.
Common Questions
What is Spinocerebellar Ataxia?
Spinocerebellar Ataxia refers to a group of inherited progressive neurological disorders characterised by degeneration of the cerebellum and its connections, causing difficulty walking, poor coordination, and speech problems. More than 40 genetic subtypes have been identified. There is currently no disease-modifying treatment, but active clinical trials are under way.
How many clinical trials are available for Spinocerebellar Ataxia?
RareWays currently indexes 136 clinical trials for Spinocerebellar Ataxia, of which 30 are actively recruiting. Trial availability changes as new studies are registered — check the trials tab for current status.
Where does the research data for Spinocerebellar Ataxia come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is updated regularly by Rocky, RareWays' automated research engine. All articles and trials link directly to their original sources.
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This information is for general awareness only.
For guidance specific to your situation, please speak with your healthcare team.