Interstitial Cystitis — Research Summary
Printed from RareWays (rareways.com.au) on 12 September 2026
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Real-world all-cause healthcare resource utilization and costs among patients with interstitial cystitis/bladder pain syndrome in the United States.
Mikl Jaromir et al. — Journal of medical economics (1 December 2026)
https://pubmed.ncbi.nlm.nih.gov/42578322/
- 2.
A pilot study of a urinary IL-8 and IL-17-based formula for discriminating Hunner-type from non-Hunner-type interstitial cystitis.
Zhou Xiangqin et al. — Cytokine (5 September 2026)
https://pubmed.ncbi.nlm.nih.gov/42700556/
- 3.
Ferroptosis and interstitial cystitis: a systematic review of preclinical evidence and molecular mechanisms.
Grigoryan Bagrat et al. — International urology and nephrology (1 September 2026)
https://pubmed.ncbi.nlm.nih.gov/41999537/
- 4.
Social Media as a Source of Information on Interstitial Cystitis/Bladder Pain Syndrome: Support Tool or Misinformation?
Gubbiotti Marilena et al. — Neurourology and urodynamics (1 September 2026)
https://pubmed.ncbi.nlm.nih.gov/42041193/
- 5.
Microbiome and chronic pelvic pain in women: a mini-review.
Vibert Jonas et al. — Human reproduction (Oxford, England) (1 September 2026)
https://pubmed.ncbi.nlm.nih.gov/42497358/
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Interstitial Cystitis
Interstitial cystitis, also called bladder pain syndrome, is a long-term condition causing pain or pressure felt in the bladder along with a frequent and urgent need to pass urine. Symptoms often flare and settle, and other causes such as infection must be ruled out first. Management is tailored to the person and may include diet and bladder training, physiotherapy, medicines, bladder instillations and procedures for Hunner lesions.
Most Recent Research
INTRODUCTION: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a persistent and heterogeneous condition diagnosed by exclusion, defined by a bladder-associated unpleasant sensation (e.g. pain, pressure, or discomfort), and affecting patients' quality of life. This real-world study aimed to describe all-cause healthcare resource utilization (HCRU) and costs associated with IC/BPS in the United States. METHODS: This matched-cohort study compared patients with an IC/BPS diagnosis to those without using real-world claims from the Merative MarketScan Commercial and Medicare Supplemental Databases (Set B; January 1, 2016-June 30, 2025). The index date was the first IC/BPS diagnosis during the identification period (January 1, 2017-September 30, 2022). During the baseline and follow-up periods, all-cause HCRU and costs (i.e. billed expenses) were reported as means per patient per year (PPPY) and rate ratios (RR). RESULTS: In the 1-year baseline period, the IC/BPS cohort demonstrated higher all-cause HCRU and costs across all categories compared with the control cohort. During the follow-up period, mean all-cause total visits were nearly 2-fold higher in the IC/BPS cohort than in the control cohort (21.78 vs. 10.94 PPPY; RR, 1.99; 95% CI, 1.95-2.04); mean all-cause total healthcare costs were also nearly 2-fold higher in the IC/BPS cohort than in the control cohort ($20,288 vs. $10,222 PPPY; RR, 1.98; 95% CI, 1.92-2.05). LIMITATIONS: This observational study of all-cause HCRU based on claims data provides insights rather than conclusions. Claims data rely on coded diagnoses and may lack information on disease severity, adherence, and indirect costs, introducing bias (e.g. diagnosis misclassification or residual confounding) and affecting the generalizability of results. CONCLUSIONS: This exploratory study demonstrated that the healthcare burden among patients diagnosed with IC/BPS remained substantial over time. These findings highlight the need for further research on cost drivers and management strategies to improve outcomes and reduce all-cause HCRU and costs among patients with IC/BPS.
Common Questions
What is Interstitial Cystitis?
Interstitial cystitis, also called bladder pain syndrome, is a long-term condition causing pain or pressure felt in the bladder along with a frequent and urgent need to pass urine. Symptoms often flare and settle, and other causes such as infection must be ruled out first. Management is tailored to the person and may include diet and bladder training, physiotherapy, medicines, bladder instillations and procedures for Hunner lesions.
How many clinical trials are available for Interstitial Cystitis?
RareWays currently indexes 157 clinical trials for Interstitial Cystitis, of which 22 are actively recruiting. Trial availability changes as new studies are registered — check the trials tab for current status.
Where does the research data for Interstitial Cystitis come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is updated regularly by Rocky, RareWays' automated research engine. All articles and trials link directly to their original sources.
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This information is for general awareness only.
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