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Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.

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ICD G72.4ORPHA:206569IMNM

Immune-Mediated Necrotising Myopathy

Immune-mediated necrotising myopathy is a rare autoimmune disease in which the immune system damages muscle fibres, causing weakness in the hips, thighs and shoulders that develops over weeks to months. It is often linked to anti-SRP or anti-HMGCR antibodies, the latter sometimes after statin use. Treatment combines steroids with other immune-suppressing medicines.

This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.

422
Articles
14
Trials (4 AU)
Data refreshed
19 October 2026
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Common Questions

What is Immune-Mediated Necrotising Myopathy?

Immune-mediated necrotising myopathy is a rare autoimmune disease in which the immune system damages muscle fibres, causing weakness in the hips, thighs and shoulders that develops over weeks to months. It is often linked to anti-SRP or anti-HMGCR antibodies, the latter sometimes after statin use. Treatment combines steroids with other immune-suppressing medicines.

How many clinical trials are available for Immune-Mediated Necrotising Myopathy?

RareWays currently indexes 14 clinical trials for Immune-Mediated Necrotising Myopathy, of which 4 are actively recruiting. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.

Where does the research data for Immune-Mediated Necrotising Myopathy come from?

RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.

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