RareWays is a research directory. It helps you understand the science. It is not medical advice. Always discuss your care options with your healthcare team.
Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.
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Hemifacial Spasm: Research Summary
Printed from RareWays (rareways.org)
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Frequency-dependent, asymmetric, and dynamic alterations of white matter function in primary hemifacial spasm: a multiband resting-state fMRI study.
Ye Haiqi et al., Brain structure & function (17 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42888348/
- 2.
Evaluation of MRI-Based Radiomic Texture Analysis and Ensemble Machine Learning Models in the Diagnosis of Hemifacial Spasm
Habip Eser Akkaya et al., Genel Tıp Dergisi (16 October 2026)
https://doi.org/10.54005/geneltip.1866460
- 3.
Phenomenology in craniofacial movement disorders: a narrative review
Jamir Pitton Rissardo et al., The Egyptian Journal of Neurology Psychiatry and Neurosurgery (12 October 2026)
https://doi.org/10.1186/s41983-026-01257-3
- 4.
Flow diversion for vertebral artery fusiform/dissecting aneurysm-related hemifacial spasm: illustrative cases.
Hashimoto Jun et al., Journal of neurosurgery. Case lessons (12 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42868617/
- 5.
Reduction in intraoperative lateral spread response as a prognostic neurophysiological parameter in microvascular decompression for hemifacial spasm: A retrospective cohort study
Setyo W. Nugroho et al., Narra X (8 October 2026)
https://doi.org/10.52225/narrax.v4i3.342
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Hemifacial Spasm
Hemifacial spasm is a rare movement disorder that causes involuntary twitching or tightening of the muscles on one side of the face. It often starts around the eye and can spread to the cheek and mouth. It is commonly caused by a blood vessel pressing on the facial nerve. Botulinum toxin injections are the usual treatment, and surgery to relieve the pressure is sometimes offered.
This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.
Most Recent Research
Primary hemifacial spasm involves central network reorganization, but white matter functional alterations remain unclear. We acquired resting-state functional magnetic resonance imaging data from 89 left-sided patients, 92 right-sided patients, and 124 healthy controls. Patients exhibited widespread abnormalities in tracts including the corpus callosum, superior longitudinal fasciculus, and corona radiata. Notably, this remodeling was highly asymmetric: left-sided patients primarily showed increased local neural activity in prefrontal pathways, whereas right-sided patients exhibited increased global network centrality across interhemispheric tracts. Furthermore, these alterations displayed distinct frequency preferences, and certain functional instabilities were exclusively captured by dynamic metrics rather than static analyses. These findings demonstrate that the disorder is associated with time-varying, frequency-specific, and asymmetric white matter functional reorganization, highlighting the value of dynamic and multi-frequency approaches in decoding its pathophysiology.
Common Questions
What is Hemifacial Spasm?
Hemifacial spasm is a rare movement disorder that causes involuntary twitching or tightening of the muscles on one side of the face. It often starts around the eye and can spread to the cheek and mouth. It is commonly caused by a blood vessel pressing on the facial nerve. Botulinum toxin injections are the usual treatment, and surgery to relieve the pressure is sometimes offered.
How many clinical trials are available for Hemifacial Spasm?
RareWays currently indexes 12 clinical trials for Hemifacial Spasm, of which 1 is actively recruiting. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.
Where does the research data for Hemifacial Spasm come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.
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This information is for general awareness only.
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