RareWays is a research directory. It helps you understand the science. It is not medical advice. Always discuss your care options with your healthcare team.

Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.

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ICD E24.0ORPHA:96253

Cushing Disease

Cushing disease is a rare hormone condition caused by a small, usually non-cancerous tumour of the pituitary gland that makes too much ACTH. This leads to excess cortisol, which can cause weight gain, easy bruising, high blood pressure, diabetes and weak bones. Surgery to remove the tumour is the main treatment, with medicines or radiotherapy used if needed.

This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.

373
Articles
37
Trials
Data refreshed
20 October 2026
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Common Questions

What is Cushing Disease?

Cushing disease is a rare hormone condition caused by a small, usually non-cancerous tumour of the pituitary gland that makes too much ACTH. This leads to excess cortisol, which can cause weight gain, easy bruising, high blood pressure, diabetes and weak bones. Surgery to remove the tumour is the main treatment, with medicines or radiotherapy used if needed.

How many clinical trials are available for Cushing Disease?

RareWays currently indexes 37 clinical trials for Cushing Disease, of which 3 are actively recruiting. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.

Where does the research data for Cushing Disease come from?

RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.

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This information is for general awareness only.

For guidance specific to your situation, please speak with your healthcare team.