Aicardi-Goutières Syndrome — Research Summary
Printed from RareWays (rareways.com.au) on 24 September 2026
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Bickerstaff Brainstem Encephalitis in a Pediatric Patient With Aicardi-Goutières Syndrome.
Mangold Sarah et al. — Pediatric neurology (1 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42617532/
- 2.
Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi-Goutières syndrome, and autism.
— Developmental medicine and child neurology (6 September 2026)
https://pubmed.ncbi.nlm.nih.gov/42702080/
- 3.
Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi-Goutières syndrome, and autism.
Shadid Omar H et al. — Developmental medicine and child neurology (19 August 2026)
https://pubmed.ncbi.nlm.nih.gov/42615359/
- 4.
Movement Disorders in Aicardi-Goutières Syndrome and Response to Immunomodulation.
Gonzalez Saez-Diez Enrique et al. — Annals of clinical and translational neurology (1 August 2026)
https://pubmed.ncbi.nlm.nih.gov/42033272/
- 5.
PTPN1 -related autoinflammation is a common cause of Aicardi-Goutières Syndrome with reduced penetrance
Daniel G. Calame et al. — medRxiv (1 April 2026)
https://doi.org/10.64898/2026.03.27.26345228
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Aicardi-Goutières Syndrome
Aicardi-Goutières syndrome is a rare inherited disorder in which the immune system behaves as though fighting a constant viral infection, causing inflammation of the brain. Signs often begin in infancy and may include irritability, seizures, stiffness and delays in development, with skin and other organs sometimes affected. Care is supportive, and medicines that dampen interferon signalling are being studied.
Most Recent Research
Common Questions
What is Aicardi-Goutières Syndrome?
Aicardi-Goutières syndrome is a rare inherited disorder in which the immune system behaves as though fighting a constant viral infection, causing inflammation of the brain. Signs often begin in infancy and may include irritability, seizures, stiffness and delays in development, with skin and other organs sometimes affected. Care is supportive, and medicines that dampen interferon signalling are being studied.
How many clinical trials are available for Aicardi-Goutières Syndrome?
RareWays currently indexes 6 clinical trials for Aicardi-Goutières Syndrome, of which 1 is actively recruiting. Trial availability changes as new studies are registered — check the trials tab for current status.
Where does the research data for Aicardi-Goutières Syndrome come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is updated regularly by Rocky, RareWays' automated research engine. All articles and trials link directly to their original sources.
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This information is for general awareness only.
For guidance specific to your situation, please speak with your healthcare team.