Transverse Myelitis — Research Summary
Printed from RareWays (rareways.com.au) on 5 April 2026
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Successful management of Pott's disease in a young woman with 32 weeks of pregnancy: a rare case report.
Maliha Afsana Rahman et al. — Radiology case reports (1 May 2026)
https://pubmed.ncbi.nlm.nih.gov/41769181/
- 2.
Overlapping autoimmunity and demyelination syndromes associated with TNF inhibitor therapy.
Daood Rula et al. — Clinical rheumatology (1 April 2026)
https://pubmed.ncbi.nlm.nih.gov/41652144/
- 3.
When Lupus Hits the Spine: A Case of Extensive Transverse Myelitis.
Diogo J et al. — Irish medical journal (19 March 2026)
https://pubmed.ncbi.nlm.nih.gov/41869999/
- 4.
Feasibility of AI-driven multichannel FES-assisted gait and cycling training in chronic neurological disorders: a case series.
Babić Nikola et al. — Journal of neuroengineering and rehabilitation (19 March 2026)
https://pubmed.ncbi.nlm.nih.gov/41857636/
- 5.
Effective Short-Interval Intravenous Immunoglobulin Reinfusion in Steroid-Unresponsive Pediatric Myelin Oligodendrocyte Glycoprotein-Associated Disease.
Alagarsamy Divya et al. — Journal of child neurology (10 March 2026)
https://pubmed.ncbi.nlm.nih.gov/41804774/
Clinical Trials — Currently Recruiting (Australia)
Ask your doctor whether you or your child may be eligible for any of these trials.
- 1.
Study of Ultomiris® (Ravulizumab) Safety in Pregnancy
Recruiting — Alexion Pharmaceuticals, Inc.
https://clinicaltrials.gov/study/NCT06312644
- 2.
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Recruiting — Sanford Health
https://clinicaltrials.gov/study/NCT01793168
- 3.
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Recruiting — Phase 1 — Sumitomo Pharma America, Inc.
https://clinicaltrials.gov/study/NCT04176198
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Transverse Myelitis
Transverse Myelitis is an inflammatory condition affecting the spinal cord that disrupts the nerve signals running through it, causing weakness, sensory disturbances, and bladder or bowel dysfunction. It can be idiopathic or a manifestation of NMOSD, MS, or other autoimmune diseases. Recovery varies widely from complete to significant permanent disability.
Most Recent Research
Spinal tuberculosis (Pott's disease) during pregnancy is rare and poses diagnostic challenges due to overlapping symptoms with pregnancy-related changes, potentially leading to severe neurological deficits if untreated. We report an 18-year-old primigravida at 32 weeks gestation presenting with progressive lower limb weakness, urinary incontinence, and upper back pain. Neurological examination showed bilateral lower limb paralysis, hypertonia, exaggerated reflexes, and sensory loss up to T10. Contrast-enhanced MRI revealed tubercular spondylo-discitis at T3-T5 with partial T4 collapse, paravertebral phlegmon, and rim-enhancing epidural abscess. Initially managed as acute transverse myelitis with methylprednisolone, the diagnosis shifted to Pott's disease based on MRI. Antituberculosis therapy with initial methylprednisolone led to rapid improvement within 4 weeks, with full neurological recovery, independent mobility, and normal delivery of a healthy infant. This case underscores MRI's pivotal role in timely diagnosis and the efficacy of conservative medical management in late pregnancy to avert irreversible complications.
This information is for general awareness only.
For guidance specific to your situation, please speak with your healthcare team.