RareWays is a research directory. It helps you understand the science. It is not medical advice. Always discuss your care options with your healthcare team.
Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.
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Hereditary Angioedema: Research Summary
Printed from RareWays (rareways.org)
For general awareness only. Not medical advice. Discuss all care options with your healthcare team.
5 Most Recent Research Articles
- 1.
Response to Letter to the Editor regarding "Matching-adjusted indirect comparison between garadacimab and lanadelumab for the long-term prophylactic treatment of patients with hereditary angioedema".
Li Yinglei et al., Journal of comparative effectiveness research (19 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42895630/
- 2.
Letter to the Editor: Matching-adjusted indirect comparison between garadacimab and lanadelumab for the long-term prophylactic treatment of patients with hereditary angioedema.
Andresen Irmgard et al., Journal of comparative effectiveness research (19 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42895650/
- 3.
Hereditary angioedema in Latin America: international recommendations, expert consensus, and reported implementation barriers
Guidos-Fogelbach G et al. (19 October 2026)
https://europepmc.org/search?query=Hereditary%20angioedema%20in%20Latin%20America%3A%20internatio
- 4.
Lonvoguran Ziclumeran - In Vivo CRISPR Gene Editing in Hereditary Angioedema.
Cohn Danny M et al., The New England journal of medicine (15 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42294842/
- 5.
Donidalorsen for the treatment of hereditary angioedema.
Horn Samantha R et al., Expert review of clinical immunology (15 October 2026)
https://pubmed.ncbi.nlm.nih.gov/42853606/
Clinical Trials : Currently Recruiting (Australia)
Ask your doctor whether you or your child may be eligible for any of these trials. Each has its ID and full eligibility criteria at the link shown.
- 1.
Donidalorsen Treatment in Children With Hereditary Angioedema
NCT07298447 · Recruiting · Phase 3 · Ionis Pharmaceuticals, Inc.
Ages 2 to 11
https://clinicaltrials.gov/study/NCT07298447
- 2.
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
NCT06960213 · Recruiting · Phase 3 · ADARx Pharmaceuticals, Inc.
Ages 18 and over
https://clinicaltrials.gov/study/NCT06960213
Source: RareWays research directory. Data from PubMed, Europe PMC, OpenAlex, ClinicalTrials.gov.
Always verify information with your healthcare team before making any decisions about your care.
Hereditary Angioedema
Hereditary angioedema is a rare genetic condition causing recurrent episodes of severe swelling in the skin, abdomen, and airway. It is caused by deficiency or dysfunction of C1 inhibitor. Untreated attacks can be life-threatening. Effective preventive and on-demand treatments are now available on the PBS.
This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.
Most Recent Research
Common Questions
What is Hereditary Angioedema?
Hereditary angioedema is a rare genetic condition causing recurrent episodes of severe swelling in the skin, abdomen, and airway. It is caused by deficiency or dysfunction of C1 inhibitor. Untreated attacks can be life-threatening. Effective preventive and on-demand treatments are now available on the PBS.
How many clinical trials are available for Hereditary Angioedema?
RareWays currently indexes 115 clinical trials for Hereditary Angioedema, of which 7 are actively recruiting. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.
Where does the research data for Hereditary Angioedema come from?
RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.
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