RareWays is a research directory. It helps you understand the science. It is not medical advice. Always discuss your care options with your healthcare team.

Coverage: 2020-01-01 onwards, with up to 300 results per query from PubMed and Europe PMC and separate limits on other sources. This is a selected index, not a complete literature search.

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ICD E27.1ORPHA:85138PAI

Addison's Disease

Addison's Disease is a rare disorder in which the adrenal glands do not produce sufficient steroid hormones, particularly cortisol and aldosterone. Affecting roughly 1 in 10,000 Australians, it requires lifelong hormone replacement therapy. Adrenal crises triggered by illness or injury can be life-threatening if not treated promptly.

This overview is general information, not an individual medical assessment. Research is selected automatically and may include mismatches. How we select and explain research.

573
Articles
14
Trials
Data refreshed
19 October 2026
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Common Questions

What is Addison's Disease?

Addison's Disease is a rare disorder in which the adrenal glands do not produce sufficient steroid hormones, particularly cortisol and aldosterone. Affecting roughly 1 in 10,000 Australians, it requires lifelong hormone replacement therapy. Adrenal crises triggered by illness or injury can be life-threatening if not treated promptly.

How many clinical trials are available for Addison's Disease?

RareWays currently indexes 14 clinical trials for Addison's Disease. These counts cover indexed trials across countries, not just your country. An Australian site does not necessarily mean that site is recruiting. Check locations, eligibility and current availability with the study team.

Where does the research data for Addison's Disease come from?

RareWays aggregates research from PubMed, Europe PMC, OpenAlex, and ClinicalTrials.gov. Data is refreshed automatically every day. All articles and trials link directly to their original sources.

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This information is for general awareness only.

For guidance specific to your situation, please speak with your healthcare team.